ASCB 50TH ANNIVERSARY ESSAY Remaining Mysteries of the Cytoplasm
نویسنده
چکیده
Nothing epitomizes the mystery of life more than the spatial organization and dynamics of the cytoplasm. How can a bunch of molecules, no matter how sophisticated, generate spatially complex behavior on a scale that is much larger than the molecules themselves? In my view, we will be done as cell biologists when we can predict the structure and dynamics of cells from DNA sequence. That goal is still some way off; indeed it is not yet clear if it is conceptually feasible. Below I identify three challenges, one general and two specific, that must be overcome if we are to make progress.
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